Researchers are searching for medications and other therapies to restore consciousness to minimally conscious and vegetative patients whose brains are still salvageable. It would be interesting to combine many or even all of these treatments to find if they have an effect on minimally conscious patients. Research on neurogenesis may lead to even more effective methods of restoring brain function to vegetative patients.
Amantadine
Apomorphine
Baclofen
Bilateral Decompressive Craniectomy
Branched Chain Amino Acids
Bromocriptine
Cranioplasty
Deep Brain Stimulation
Emotional Visual Stimulation
Extradural Cortical Stimulation
Full Caloric Intake
GABA Agonists
Hyperbaric Oxygen
Intracranial Pressure-Targeted Therapy
L-dopa
Median Nerve Stimulation
Music Therapy
Near-Infrared LED Therapy
Repetitive Transcranial Magnetic Stimulation
Social Tactile Interaction
Spinal Cord Stimulation
Zolpidem
References:
A case of primary brain-stem injury recovered from persistent vegetative state after L-dopa administration. (Link)
A long-term intensive behavioral treatment study in patients with persistent vegetative state or minimally conscious state. (Link)
Amantadine: a potential treatment for the minimally conscious state. (Link)
An unexpected recovery from permanent vegetative state. (Link)
Awakenings from persistent vegetative state: report of three cases with parkinsonism and brain stem lesions on MRI. (Link)
Behavioral and neurophysiological effects of repetitive transcranial magnetic stimulation on the minimally conscious state: a case study. (Link)
Branched-chain amino acids may improve recovery from a vegetative or minimally conscious state in patients with traumatic brain injury: a pilot study. (Link)
Clinical study on effect of HBO plus electric stimulation on treatment for the vegetative state. (Link)
Continuous subcutaneous apomorphine for severe disorders of consciousness after traumatic brain injury. (Link)
Cortical activity after emotional visual stimulation in minimally conscious state patients. (Link)
DBS therapy for a persistent vegetative state: ten years follow-up results. (Link)
DBS therapy for the vegetative state and minimally conscious state. (Link)
Deep brain stimulation for the treatment of vegetative state. (Link)
Deep brain stimulation therapy for a persistent vegetative state. (Link)
Deep brain stimulation therapy for the vegetative state. (Link)
Effect of early nutritional support on intensive care unit length of stay and neurological status at discharge in children with severe traumatic brain injury. (Link)
Effects of musicokinetic therapy and spinal cord stimulation on patients in a persistent vegetative state. (Link)
Fast awakening from minimally conscious state with apomorphine. (Link)
Focal increase in cerebral blood flow after treatment with near-infrared light to the forehead in a patient in a persistent vegetative state. (Link)
HRV response of vegetative state patient with music therapy. (Link)
Incidence of clinically significant responses to zolpidem among patients with disorders of consciousness: a preliminary placebo controlled trial. (Link)
Increased arousal in a patient with anoxic brain injury after administration of zolpidem. (Link)
Intrathecal administration of GABA agonists in the vegetative state. (Link)
Intrathecal baclofen in patients with persistent vegetative state: 2 hypotheses. (Link)
Late recovery from post-traumatic vegetative state. (Link)
Levodopa treatment for patients in persistent vegetative or minimally conscious states. (Link)
Modified Lund concept versus cerebral perfusion pressure-targeted therapy: a randomised controlled study in patients with secondary brain ischaemia. (Link)
Placebo-controlled trial of amantadine for severe traumatic brain injury. (Link)
Positive outcomes in traumatic brain injury-vegetative state: patients treated with bromocriptine. (Link)
Predictors of outcome in prolonged posttraumatic disorders of consciousness and assessment of medication effects: A multicenter study. (Link)
Prognosis for severe traumatic brain injury patients treated with bilateral decompressive craniectomy. (Link)
Repetitive transcranial magnetic stimulation-associated neurobehavioral gains during coma recovery. (Link)
The place of L-dopa/carbidopa in persistent vegetative state. (Link)
Therapeutic time window for musicokinetic therapy in a persistent vegetative state after severe brain damage. (Link)
Transient reversal of anoxic brain injury-related minimally conscious state after zolpidem administration: a case report. (Link)
Use of hyperbaric oxygen in traumatic brain injury: retrospective analysis of data of 20 patients treated at a tertiary care centre. (Link)
Vegetative state and minimally conscious state: a review of the therapeutic interventions. (Link)
