Perfect Health Diet is a book written by two scientists who combed through massive amounts of scientific research. Their goal was to find a diet that would heal their medical problems and optimize health and longevity.
The two authors are:
• Dr. Paul Jaminet: an astrophysicist who worked at the Harvard-Smithsonian Center for Astrophysics and who is currently a management consultant
• Dr. Shou-Ching Jaminet: a molecular biologist and cancer researcher at Harvard Medical School
Perfect Health Diet is one of the most extensively researched books ever written about nutrition. It has over 600 research citations, with many of them referencing articles in nutrition journals and medical databases. The book is also suitable for a wide audience. Readers who want quick answers can skim certain sections and come away with actionable steps that are easy to implement. Scientists and physicians and nutrition hobbyists can dig into further technical information provided in other sections. I definitely recommend buying the book. More information on the contents of the book is at this page on the Perfect Health Diet blog: Buy Our Book
Here are some of my notes on what the book covers:
• Most diseases and forms of ill health are caused by food toxins, malnourishment, and chronic infections.
• By calories, the Perfect Health Diet is made up of 20% carbohydrates, 65% fat, and 15% protein. By weight, the diet is about 65% plant foods and 35% meats and oils.
• 20% of calories (about 1.5 lbs per day) in the Perfect Health Diet comes from safe starches like sweet potatoes, white rice, and berries. Also, feel free to eat as many vegetables as you want, but don’t count calories from them. 80% of calories (about 1 lb per day) comes from healthy fat (fatty meat, seafood, eggs) and around 4 tablespoons of healthy oils and fats.
• Foods to eat: starchy tubers, white rice, fruits, berries, vegetables, seaweed, fatty meats, seafood, eggs, butter, cream, ice cream, sour cream, lard, tallow, coconut oil, olive oil, nuts, cheeses, yogurt, and spices.
• Foods to avoid: grains and cereals (wheat, oats, corn, other grains, bread, pasta), sugar, corn syrup, soda, candy, legumes (soybeans, kidney beans, pinto beans, peanuts), omega-6-rich vegetable seed oils (soybean oil, corn oil, safflower oil, peanut oil, canola oil), pasteurized milk, and dry lean meats
• Supplements to take: multivitamin, vitamin C, vitamin D3, vitamin K2, magnesium, selenium, iodine, copper, and chromium
• Practice intermittent fasting through strategies like restricting eating to an eight hour time period each day, or through occasional ketogenic fasting by eating lots of coconut oil while temporarily avoiding carbs and protein.
• The Perfect Health Diet prevents and may even cure diseases like heart disease, cancer, dementia, autoimmune diseases, fatigue, acid reflux, graying hair, etc.
• Hunter gatherers ate diets consisting of 5% to 35% carbohydrate, 50% to 70% fat, and 15% to 25% protein.
• Mother’s milk is a complete food for infants, and it has a ratio by calories of 39% carbs, 54% fat, and 7% protein.
• Mice that were designed to develop diabetes became highly resistant to the disease when they ate a diet consisting of 5.6% carbohydrates, 82.5% fat, and 12.0% protein.
• The Perfect Health Diet optimizes bodily nutrition, minimizes stress on the gut and liver, and is robust against dietary failure by providing redundant sources of nutrients.
• The Perfect Health Diet minimizes the risk of glucose deprivation, keeps blood glucose levels low, manufactures ketones that nourish neurons and protect against glucose deficiency, and limits toxins.
• Ketogenic diets are potential treatments for epilepsy, schizophrenia, bipolar disorder, depression, psychoses, migraines, solid tumor cancers, diabetes, metabolic syndrome, obesity, bacterial infections, atherosclerosis, Alzheimer’s, Parkinson’s, multiple sclerosis, Lyme disease, fibromyalgia, and neuropathies.
• To make the diet ketogenic, eat about 200 calories from safe starches like sweet potato and the rest of the calories from coconut oil.
• A long-term ketogenic diet is only recommended as a treatment for certain diseases. For healthy people, occasional days of ketogenic fasts are helpful.
• Adding 26 pounds of muscle per year requires only 5 grams (20 calories) of protein per day. Controlled trials have not found any additional muscle gain from higher protein consumption.
• Whey protein contains branched chain amino acids, which increase muscle growth and help heal the gut.
• Too much protein intake can lead to ammonia poisoning.
• In animal studies, restricting protein leads to longer lifespans.
• Most cells prefer fats over glucose for energy, since fats burn cleanly while glucose produces reactive oxygen species that can damage cells.
• Eating a purely carnivorous diet can lead to stress on the liver, toxicity, reduced longevity, risk of glucose deprivation, dry eyes, and gastrointestinal cancers.
• To avoid glucose deprivation, it’s important to eat at least 200 carb calories per day, eat at least 600 calories per day of carbs and protein, and include coconut oil and fiber in the diet.
• It’s important to keep glucose consumption in a sweet spot near the body’s glucose needs, as carb consumption above those needs can lead to hyperglycemia and hyperinsulinemia.
• Hyperglycemia can lead to nerve damage, organ damage, bacterial infections, cancer progression, and increased mortality.
• For a good lipid profile, keep dietary carbs below 600 calories per day.
• The optimal fatty acid ratios are 10% of fat calories (6.5% of total calories) from short-chain fatty acids, 75-80% of fat calories (50% of total calories) from long-chain saturated fatty acids and monounsaturated fatty acids, and 10-15% of fat calories (7-10% of total calories) from omega-6 and omega-3 polyunsaturated fatty acids.
• An excess of omega-6 fatty acids is linked to heart disease, cancer, stroke, obesity, inflammation, immune system suppression, mental illness, arthritis, asthma, headaches, menstrual cramps. osteoporosis, allergies, ulcerative colitis, and increased mortality.
• Some ways to bring PUFA levels near the optimum are: avoiding vegetable seed oils and foods prepared with them, eating meats low in omega-6 (like beef and lamb), and eating about a pound of salmon a week to balance omega-3 and omega-6 tissue levels.
• In animal studies, omega-6 PUFA lead to negative health effects, whereas saturated fats have beneficial health effects since they are immune to the oxidizing effect of sugars.
• High omega-3 intake (such as 6.5 g/day or 5 lbs of salmon per week) may increase the risk of hemorrhagic stroke. Intakes less than 3 g/day are safe.
• Fish oil capsules don’t prevent cardiac death, but fish consumption is preventive. Fish oil capsules can easily become rancid.
• Saturated and monounsaturated fatty acids are nontoxic and safe in large amounts.
• High dietary intake of saturated and monounsaturated fatty acids reduces the risk of heart disease, increases muscle mass, and increases body temperature (which is useful for fighting infections).
• A high intake of saturated and monounsaturated fat leads to muscle gain by increasing testosterone levels, inhibiting muscle breakdown, and promoting the release of growth hormone.
• Short-chain fats like coconut oil protect the brain, protect against cancer, have antimicrobial properties, improve blood lipids, and promote weight loss.
• Blueberries reduce pathogenic bacteria while increasing probiotic bacteria. Blueberry husks with probiotics increase butyrate levels in the blood. Starches (potato, taro, white rice, sago) as well as squashes and stalk vegetables may also generate butyrate. Butyrate prevents obesity, heals the intestine, improves gut barrier integrity, relieves constipation, helps prevent colon cancer, delays neurodegeneration, improves cardiovascular health, stabilizes blood glucose levels, reduces inflammation, and promotes tissue healing.
• People with damaged guts might benefit from limiting fiber.
• Combine starches with fats in a ratio of one-third carbs to two-thirds fats.
• Make sure meat is fatty and moist instead of lean and dry. Lean meats should be combined with a fatty food.
• Eat two to three times as much plant food (as measured by weight) in relation to meat.
• Carb calories (about 300 per day) should be from safe starches like taro, sweet potatoes, yams, potatoes, white rice, white rice noodles, or white rice crackers.
• Avoid commercial foods until food producers start using healthier cooking oils.
• Raspberries, papaya, banana, and strawberries have a high potassium to fructose ratio (which indicates a healthy fruit or berry).
• Spices and salt are beneficial, but extremely hot spices can damage the digestive tract.
• Grass-fed meat, eggs from grass-fed chickens, and wild fish have lower omega-6 levels.
• Macadamia nuts have the lowest omega-6 content out of all tree nuts.
• All plants have toxins, so it is safer to eat small quantities from a wide variety of plants rather than large amounts of a single species.
• Cereal grains impair digestion, lead to inflammation, trigger autoimmune diseases, make the body susceptible to infectious diseases, damage heart tissue, promote cancer, cause neuropathy, cause rickets, lead to acid reflux, promote kidney disease, lead to stomach ulcers, increase the likelihood of a heart attack, and increase mortality.
• Wheat has opioids that cause tumor cells to multiply, cause schizophrenia, and feminize male bodies.
• Legumes have negative digestive effects including leaky gut, bad digestion, diarrhea, and bloating. Legumes also cause stunted growth, organ dysfunction, heart disease, tendon damage, and allergies.
• Vegetable oils lead to cardiovascular disease, liver damage, and immune system dysfunction.
• Fructose interacts with polyunsaturated fats to generate toxins, so fruit should be eaten on an empty stomach between meals and eaten only with cream or coconut oil. Breakfast may be the safest time to eat fruit due to the overnight fast and glycogen depletion.
• High fructose corn syrup and sugar lead to DNA damage, faster aging, stiff joints, aged skin, high blood pressure, heart attacks, bad lipid profiles, metabolic syndrome, diabetes, non-alcoholic fatty liver disease, pancreatitis, obesity, impaired memory, organ damage, bacterial infections, cirrhosis, fetal insulin resistance, gout, and kidney disease.
• Avoid sugar-cured meats, which have advanced glycation endproducts. Uncured bacon is fine.
• People who have arthritis may benefit from avoiding nightshades (eggplant, tomato, peppers, and potato).
• Potatoes should be kept continuously in a cool dark environment.
• It’s safest to cook meats a lower temperatures, which prevents the formation of toxic compounds.
• Good drinks are tea, coffee, water, cream, and wine.
• The Perfect Health Diet is very similar to the traditional Pacific islander diet. Pacific islanders such as Okinawans, Kitavans, and Hawai’ians who ate the traditional diet had exceptional health and life expectancy.
• Supplements are useful, since modern people are malnourished (due to sedentary lifestyles, nutrient-poor modern foods, food production, modern cooking, and antinutrients). Even paleolithic humans may have been malnourished.
• Malnourishment leads to reduced health and lower IQ among offspring of malnourished parents.
• Multivitamins are useful, but only if vitamin D and vitamin K2 status is optimized.
• Vitamin D reduces the incidence of cancer, cardiovascular disease, respiratory disease, diabetes, intracellular pathogens, dementia, multiple sclerosis, and mortality from all causes. 3,000 to 5,000 IU of vitamin D (from both sun and supplements) is a good amount. 25OHD levels should be around 40 ng/ml.
• Vitamin K2 helps prevent hemorrhage, fractures, atherosclerosis, joint disease, cancer, cognitive decline, and vitamin D toxicity. 100 mcg of vitamin K2 per day is a good recommended amount.
• Selenium and iodine promote thyroid health, improve immune function, and help prevent cancer. Iodine intake should start at 1 mg/day or less and be upped gradually to give the thyroid time to adapt. To prevent selenium toxicity, 200 mcg/day is the recommended amount.
• Magnesium leads to significant reductions in cardiovascular mortality and improves immune function. A good magnesium intake is 400 mg/day to 800 mg/day.
• Eating a quarter-pound of beef or lamb liver per week provides enough copper, which most people are deficient in.
• Chromium improves immune function and helps prevent cardiovascular disease. 200 mcg/day of chromium is safe and beneficial.
• Vitamin C decreases mortality from all causes and increases lifespan. Vitamin C supplements in the range of 500 mg to 1 g per day are beneficial.
• Some supplements to avoid are vitamin A, calcium, zinc, niacin, vitamin E, folic acid, and fish oil capsules.
• There are thousands of toxins and hundreds of pathogens which can cause diseases. It may be important to take antibiotics to cure chronic diseases.
• Pathogens are associated with atherosclerosis, stroke, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, mood disorders, cancer, multiple sclerosis, arthritis, rosacea, and other diseases.
• The Perfect Health Diet and supplements provide support to important immune system components and actions such as antimicrobial peptides, respiratory bursts, autophagy, and protein restriction.
• Ketogenic fasts with coconut oil promote autophagy, which is very effective in fighting pathogens.
• Melatonin promotes muscle growth, kills tumor cells, protects against infections, and is effective in treating some diseases (irritable bowel syndrome, high blood pressure, macular degeneration, glaucoma, and diabetes).
• Exercise and diaphragmatic breathing are effective for reducing stress and strengthening immune function by lowering cortisol levels.
• Ways to lose weight: eliminating omega-6 oils, cutting fructose intake, giving up wheat and other cereal grains, normalizing thyroid function (with iodine, selenium, and vitamin D supplements), eating nutrient-rich foods, and having intermittent fasts
• Ways to accelerate weight loss: spending time in cold temperatures, spending more time on your feet, exercising at high intensity twice a week, eating coconut oil, getting a good night’s sleep, drinking lots of water, and getting a fecal transplant from a slender person if necessary
• People who have lifespans of greater than 110 years tend to follow high fat/low-carb diets, calorie restriction, and intermittent fasting.